Hypokalemia, or low blood potassium levels, can indeed be a serious condition that, in severe cases, can lead to death. Potassium is a critical electrolyte that helps regulate the electrical activity of the heart, among other functions. When potassium levels drop too low, it can cause a variety of cardiac issues, including arrhythmias, which are irregular heartbeats. In some cases, severe arrhythmias can lead to cardiac arrest, which is a life-threatening condition. In the context of cardiac patients, hypokalemia can be exacerbated by certain treatments, such as diuretics, which increase the loss of potassium through the kidneys. As you've mentioned, in hypertension, the use of nonpotassium-sparing diuretics is associated with an increased risk of cardiac arrest and death. It's important for healthcare providers to monitor potassium levels closely in patients on such medications and to adjust treatment as necessary to maintain a safe and healthy balance of electrolytes. read more >>

In cardiac patients, hypokalemia and potassium depletion are often caused by an increased loss of potassium through the kidneys due to nonpotassium-sparing diuretic therapy. ... In hypertension, diuretic therapy is associated with an increased risk of cardiac arrest and death (14,15).read more >>