As a subject matter expert in medical conditions, I can provide you with the information regarding the criteria for lupus. The American College of Rheumatology has established a set of criteria for the classification of systemic lupus erythematosus (SLE). These criteria are used for diagnostic purposes and are not the same as diagnostic criteria. Here are the 11 criteria:
1.
Malar rash: A flat or raised red rash on the cheeks, which may spread to the bridge of the nose.
2.
Discoid rash: A round, scaly, red rash with a raised edge, typically on the face, ears, or scalp.
3.
Photosensitivity: Skin rash as a result of sun exposure.
4.
Oral ulcers: Painless sores in the mouth or nose, often preluded by increased pain or sensitivity.
5.
Arthritis: Non-erosive arthritis involving two or more peripheral joints.
6.
Serositis: Inflammation of the lining of the lungs (pleurisy) or the heart (pericarditis).
7.
Renal disorder: Persistent protein or cellular casts in the urine or a renal biopsy indicating lupus nephritis.
8.
Neurological disorder: Seizures or psychosis in the absence of drug or metabolic causes.
9.
Hematological disorder: Hemolytic anemia, leukopenia (WBC < 4000/mm³ on two or more occasions), lymphopenia (lymphocytes < 1500/mm³ on two or more occasions), or thrombocytopenia (platelets < 100,000/mm³).
10.
Immunological disorder: Positive anti-dsDNA antibody, anti-Sm antibody, or false-positive test for syphilis that does not become negative with treatment and is confirmed by the FTA-ABS or MHA-TP test.
11.
Antinuclear antibody (ANA): An abnormal level of antinuclear antibodies in the blood, as measured by an immunofluorescent ANA test at greater than 1:160 (reference: ANA IF > 1:160).
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