As a healthcare professional, I must emphasize that it's crucial to consult with a doctor or pharmacist before combining any pain medication with blood thinners. This is because certain medications can interact with blood thinners and affect their effectiveness or cause adverse effects. Generally, over-the-counter (OTC) pain relievers like acetaminophen (Tylenol) are considered safe to take with blood thinners, as they do not have an impact on blood clotting. However, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin) and aspirin can interact with blood thinners and are typically not recommended unless under close medical supervision. It's important to note that even though acetaminophen is often safe, it can still cause liver problems if not taken as directed. Always follow the dosing instructions and discuss any potential interactions with your healthcare provider. read more >>

These over-the-counter painkillers -- called nonsteroidal anti-inflammatory drugs (NSAIDs) -- include such drugs as Advil, Aleve, Bufferin, Excedrin, Motrin and Nuprin, as well as aspirin. Patients who use blood thinners such as warfarin, Eliquis, Xarelto or Pradaxa should not take them, the researchers said.read more >>