Hello, I'm an expert in the field of cellular biology and human physiology. When the body is dehydrated, several changes occur at the cellular level that can impact overall health and function.

Firstly, dehydration leads to a decrease in the volume of the extracellular fluid, which can cause cells to shrink as they lose water. This shrinkage can affect the cell's ability to perform its normal functions.

Secondly, the concentration of solutes in the extracellular fluid increases, which can disrupt the osmotic balance. Cells may lose or gain water in an attempt to maintain their internal balance, which can lead to cellular dysfunction.

Thirdly, dehydration can impair the efficiency of the circulatory system. Blood volume may decrease, reducing the delivery of oxygen and nutrients to cells and the removal of waste products.

Additionally, the body's ability to regulate temperature is compromised, as sweating, which is a key cooling mechanism, is reduced. This can lead to an increase in body temperature, which can stress cells and potentially damage proteins and other cellular structures.

Finally, the lack of water can also affect the kidneys' ability to produce urine efficiently, leading to a buildup of waste products in the body, which can be toxic to cells.

In summary, dehydration has a range of negative effects on cells, from direct physical changes to disruptions in the body's homeostatic mechanisms.

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As you 'lose' body water without replacing it, your blood becomes more concentrated and, at a point, this triggers your kidneys to retain water. The result: you urinate less. ... At a cellular level, 'shrinkage' occurs as water is effectively borrowed to maintain other stores, such as the blood.read more >>