As a subject matter expert in comic book lore and superhero narratives, I can provide an analysis of characters who might be able to stand against Deadpool in the Marvel Universe.

Deadpool, whose real name is Wade Wilson, is known for his regenerative healing factor, which allows him to recover from virtually any wound, making him extremely difficult to defeat. However, there are several characters who could potentially beat him:


1. Thanos with the Infinity Gauntlet: With the power of all six Infinity Stones, Thanos could simply erase Deadpool from existence or incapacitate him in a way that his healing factor couldn't overcome.


2. Doctor Strange: As the Sorcerer Supreme, Doctor Strange could potentially trap Deadpool in a time loop or an alternate dimension where his healing factor would be neutralized.


3. Adam Warlock with the Soul Gem: The Soul Gem has the power to manipulate life and death, which could potentially control or negate Deadpool's healing factor.


4. Galactus: As a cosmic entity, Galactus could potentially find a way to neutralize Deadpool's powers or simply outpower him.


5. Phoenix Force: The Phoenix Force, particularly when bonded with a powerful host, has shown the ability to rewrite reality and could potentially alter Deadpool's existence.


6. Immortal characters like Squirrel Girl: While it may seem unlikely, Squirrel Girl has a history of defeating powerful opponents, and her ability to communicate with squirrels could potentially lead to a strategy that outsmarts Deadpool.

7.
Heroes with reality-warping abilities: Characters like Mr. Mxyzptlk or Franklin Richards could potentially alter reality to defeat Deadpool.

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Deadpool is immortal. the only way to kill him would be through thanos removing the curse, then striking his healing factor with carbonadium OR complete atomization. Although, marvel revealed they will be killing him.read more >>