As a neuroscientist with a focus on brain disorders, I can provide you with information on the symptoms associated with white matter diseases in the brain. White matter in the brain is composed of nerve fibers that facilitate communication between different areas of the brain. Damage to these areas can result from various conditions, such as multiple sclerosis (MS), which is a common cause of white matter disease. Symptoms of white matter disease can vary widely depending on the specific condition and the location of the damage within the brain. However, some common symptoms include: 1. Numbness: This can occur in various parts of the body and is often one of the first symptoms of MS. 2. Weakness: Muscle weakness can affect limbs or other body parts and may progress over time. 3. Fatigue: This is a common symptom in many white matter diseases and can be debilitating. 4. Memory Loss: Cognitive functions, such as memory, can be affected, leading to problems with recall and learning new information. 5. Cognitive Dysfunction: This is a broad term that encompasses various cognitive impairments, including memory loss, difficulty with problem-solving, and slowed information processing. It's important to note that while these symptoms are common, they do not necessarily occur in every case of white matter disease, and the severity can vary greatly from person to person. read more >>

��In general, white matter disease causes acute MS symptoms like numbness and weakness," Stone says. "Gray matter disease causes progressive symptoms like fatigue and memory loss. These higher brain functions are called cognitive functions. Most MS disability actually comes from cognitive dysfunction."read more >>