Immunotherapy is a type of cancer treatment that uses the body's immune system to fight cancer cells. There are several types of immunotherapy, including immune checkpoint inhibitors, which are designed to enhance the immune system's ability to recognize and attack cancer cells. PD-1 inhibitors and CTLA-4 inhibitors are two types of immune checkpoint inhibitors.
PD-1 inhibitors treat a range of cancers by blocking the PD-1 protein, which cancer cells use to protect themselves from being attacked by the immune system. These inhibitors have been used successfully to treat
melanoma,
non-small-cell lung cancer,
kidney cancer,
bladder cancer, head and
neck cancers, and
Hodgkin's lymphoma.
CTLA-4 inhibitors work by turning off a checkpoint called CTLA-4, which is also found on
T cells. This allows the immune system to attack cancer cells more effectively. One CTLA-4 inhibitor is currently being used for
melanoma, and others are being investigated for their potential use in treating other types of cancer.
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