Hello, I'm a pharmacist with a strong background in clinical practice and pharmaceutical sciences. I'm here to explain how steroid creams work.

Steroid creams, also known as topical corticosteroids, are medications that are used to treat a variety of skin conditions. They work by reducing inflammation, itching, and redness associated with these conditions. Here's a step-by-step breakdown of how they function:


1. Application: The steroid cream is applied directly to the affected skin area.

2. Absorption: The cream is absorbed through the skin's surface into the underlying tissues.

3. Inflammation Reduction: The active ingredients in the steroid cream, which are synthetic forms of the hormone cortisol, bind to cortisol receptors in the skin cells.

4. Gene Expression: Once bound, these receptors change the way skin cells function, particularly in terms of gene expression related to inflammation.

5. Anti-Inflammatory Action: This leads to a decrease in the production of inflammatory mediators, which are chemicals that cause inflammation, redness, and swelling.

6. Healing Process: With less inflammation, the body's natural healing processes can take place more effectively.

It's important to note that steroid creams are potency classified, with higher potency creams being more effective but also carrying a higher risk of side effects. They should be used according to a healthcare provider's instructions to ensure safety and effectiveness.

read more >>

Typically, steroid creams are used to reduce skin inflammation caused by conditions such as psoriasis and eczema. ... They work by preventing cells from producing inflammation-causing chemicals that are released in response to a variety of different triggers.read more >>