As a medical professional with expertise in nephrology, I can tell you that kidney disease can be a serious condition that affects the functioning of the kidneys. When the kidneys are not able to filter waste products effectively, it can lead to a buildup of toxins in the body. If the condition progresses to end stage renal failure (ESRF), it becomes life-threatening because the kidney function is severely compromised. Without intervention, such as dialysis or a kidney transplant, a person with ESRF is at high risk of dying within a short period of time. It's important to manage blood pressure and other related health issues to slow the progression of the disease and to seek appropriate medical treatment to improve the quality and longevity of life. read more >>

If the kidneys fail the filtering must be done artificially and your blood pressure may have to be controlled by medication. End stage renal failure (ESRF) is when kidney function is so bad that you are likely to die within weeks or months unless special treatment such as dialysis or transplantation is given.read more >>