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Why does Addison's disease cause skin darkening 2024?
caused hyperpigmentation caused
Questioner：Lucas Lee 2023-05-28 12:25:02
The most authoritative answer in 2024
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Charlotte Clark——Studied at the University of Zurich, Lives in Zurich, Switzerland.
It is caused by the stimulant effect of excess adrenocorticotrophic hormone (ACTH) on the melanocytes to produce melanin. The hyperpigmentation is caused by high levels of circulating ACTH that bind to the melanocortin 1 receptor on the surface of dermal melanocytes.Feb 13, 2018read more >>+119962023-06-07 12:25:02
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