As a medical expert, it is important to understand that lupus, also known as systemic lupus erythematosus (SLE), is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, and internal organs. The immune system, which normally protects the body from infection, mistakenly attacks healthy tissues, causing inflammation and potentially leading to a range of symptoms.

One of the ways lupus can manifest is through its impact on the endocrine system, particularly the thyroid gland. The thyroid is a small, butterfly-shaped gland located at the base of the neck. It plays a crucial role in regulating the body's metabolism, which is the process by which the body converts food into energy and maintains other vital functions.

When lupus affects the thyroid, it can lead to the development of autoimmune thyroid disease. There are two primary types of autoimmune thyroid diseases: Hashimoto's thyroiditis, which causes the thyroid to underproduce hormones (hypothyroidism), and Graves' disease, which causes the thyroid to overproduce hormones (hyperthyroidism). Both conditions can have a significant impact on weight.

In the case of hypothyroidism, the thyroid gland does not produce enough thyroid hormones, which can slow down the body's metabolism. A slower metabolism means that the body burns fewer calories at rest and may struggle to lose weight or even gain weight despite eating the same amount of food and maintaining the same level of physical activity as before. This can lead to unexplained weight gain, which is a common concern among individuals with lupus.

On the other hand, hyperthyroidism, which is less common in lupus patients, causes the thyroid to produce too much thyroid hormone. This can speed up the metabolism, leading to weight loss. However, it is important to note that the weight loss associated with hyperthyroidism is often unwanted and can be a sign of an underlying health issue that requires medical attention.

In addition to thyroid-related issues, lupus itself can also cause weight gain through several mechanisms. For instance, the inflammation associated with lupus can lead to fluid retention, which can contribute to weight gain. Furthermore, the use of certain medications to manage lupus symptoms, such as corticosteroids, can also cause weight gain as a side effect.

It is also worth noting that lupus can cause fatigue, which may lead to a decrease in physical activity levels. A reduction in activity can contribute to weight gain, especially when combined with other factors such as a slowed metabolism or medication side effects.

In conclusion, lupus can indeed cause weight gain through various mechanisms, including the development of autoimmune thyroid disease, inflammation and fluid retention, the use of certain medications, and changes in physical activity levels due to fatigue. It is essential for individuals with lupus to work closely with their healthcare providers to manage their symptoms and address any concerns related to weight changes.

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It's not uncommon for people with lupus to develop autoimmune thyroid disease. The thyroid helps control your body's metabolism. A poorly functioning thyroid can affect vital organs like your brain, heart, kidneys, and liver. It can also result in weight gain or weight loss.Apr 5, 2017read more >>