As a healthcare professional with expertise in pharmacology, I can provide you with information regarding the potential side effects of metoprolol, a medication commonly used to treat high blood pressure, angina, and heart rhythm disorders. Metoprolol is a beta-blocker, and while weight gain is not a common side effect typically listed for this class of drugs, it is possible for some individuals to experience this. Weight gain can occur as a result of several factors, including: 1. Fluid Retention: Beta-blockers like metoprolol can sometimes cause the body to retain fluids, which may lead to a temporary increase in weight. 2. Decreased Physical Activity: Metoprolol can cause fatigue or reduced exercise tolerance, which might lead to a more sedentary lifestyle and, consequently, weight gain. 3. Appetite Changes: Some people might experience an increase in appetite while on metoprolol, which could lead to consuming more calories and weight gain. It's important to note that not everyone will experience these side effects, and the likelihood of weight gain can vary from person to person. If you are concerned about weight gain while taking metoprolol, it's crucial to discuss this with your healthcare provider. They can monitor your situation, consider any necessary adjustments to your medication regimen, or recommend lifestyle changes to help manage your weight. read more >>

Yes. Weight gain can occur as a side effect of some beta blockers, especially the older ones, such as atenolol (Tenormin) and metoprolol (Lopressor, Toprol-XL). The average weight gain is about 2.6 pounds (about 1.2 kilograms). ... Doctors aren't sure exactly why some beta blockers cause weight gain.read more >>