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Which antibiotics cause QT prolongation?
Macrolide antibiotics Fluoroquinolones Tetracyclines
Questioner：Ethan Henderson 2018-04-06 09:59:14
The most authoritative answer in 2024
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Ethan Hall——Works at the International Renewable Energy Agency, Lives in Abu Dhabi, UAE.
As a medical professional with expertise in pharmacology, I can provide you with information on antibiotics that are known to potentially cause QT prolongation, which is a heart rhythm abnormality that can be life-threatening. Several antibiotics have been associated with QT prolongation, including but not limited to: 1. Macrolide antibiotics: Erythromycin, clarithromycin, and azithromycin. 2. Fluoroquinolones: Levofloxacin, moxifloxacin, and ciprofloxacin. 3. Tetracyclines: Gatifloxacin (which has been withdrawn in some countries due to safety concerns). 4. Antifungal medications: Voriconazole and posaconazole. 5. Others: Telithromycin (also withdrawn from the market due to safety concerns), linezolid, and isepamicin. It's important to note that not all patients will experience QT prolongation while taking these medications, and the risk can be influenced by factors such as dosage, duration of treatment, underlying health conditions, and the presence of other medications that can also affect the QT interval. read more >> -
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Gabriel Ross——Works at Shopify, Lives in Ottawa, Canada
Antimicrobials. Macrolides (erythromycin, clarithromycin), fluoroquinolones, antifungals, and antimalarials have been implicated in predisposing to TdP as a result of QT prolongation.read more >>
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